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Redirecting an Anticancer to an Antibacterial Hit Against Methicillin-Resistant Staphylococcus aureus
YM155 is a clinically evaluated anticancer with a fused naphthoquinone-imidazolium scaffold. In this study, we demonstrated that based on weak or cryptic antibacterial activity of YM155 against methicillin-resistant Staphylococcus aureus (MRSA) (MIC of 50 μg/ml), some congeneric compounds with short...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398426/ https://www.ncbi.nlm.nih.gov/pubmed/30858845 http://dx.doi.org/10.3389/fmicb.2019.00350 |