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Zebrafish duox mutations provide a model for human congenital hypothyroidism

Thyroid dyshormonogenesis is a leading cause of congenital hypothyroidism, a highly prevalent but treatable condition. Thyroid hormone (TH) synthesis is dependent on the formation of reactive oxygen species (ROS). In humans, the primary sources for ROS production during thyroid hormone synthesis are...

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Detalles Bibliográficos
Autores principales: Chopra, Kunal, Ishibashi, Shoko, Amaya, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398463/
https://www.ncbi.nlm.nih.gov/pubmed/30700401
http://dx.doi.org/10.1242/bio.037655