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Spatial positioning of EB family proteins at microtubule tips involves distinct nucleotide-dependent binding properties

EB proteins track the ends of growing microtubules and regulate microtubule dynamics both directly and by acting as the hub of the tip-tracking network. Mammalian cells express cell type-specific combinations of three EB proteins with different cellular roles. Here, we reconstitute EB1, EB2 and EB3...

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Detalles Bibliográficos
Autores principales: Roth, Daniel, Fitton, Benjamin P., Chmel, Nikola P., Wasiluk, Natalia, Straube, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398475/
https://www.ncbi.nlm.nih.gov/pubmed/30262468
http://dx.doi.org/10.1242/jcs.219550