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hnRNP A1 antagonizes cellular senescence and senescence‐associated secretory phenotype via regulation of SIRT1 mRNA stability
Senescent cells display a senescence‐associated secretory phenotype (SASP) which contributes to tumor suppression, aging, and cancer. However, the underlying mechanisms for SASP regulation are not fully elucidated. SIRT1, a nicotinamide adenosine dinucleotide‐dependent deacetylase, plays multiple ro...
Autores principales: | Wang, Hui, Han, Limin, Zhao, Ganye, Shen, Hong, Wang, Pengfeng, Sun, Zhaomeng, Xu, Chenzhong, Su, Yuanyuan, Li, Guodong, Tong, Tanjun, Chen, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398525/ https://www.ncbi.nlm.nih.gov/pubmed/27613566 http://dx.doi.org/10.1111/acel.12511 |
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