SIRT1‐mediated ERβ suppression in the endothelium contributes to vascular aging

SIRT1 has many important molecular functions in aging, and the estrogen receptors (ERs) have a vasculoprotective effect, although the detailed mechanism for the roles of SIRT1 and ERs in vascular aging remains unclear. We found that ERβ expression in the endothelium was reduced in aging mice, and th...

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Detalles Bibliográficos
Autores principales: Kong, Danli, Zhan, Ying, Liu, Zhaoyu, Ding, Ting, Li, Min, Yu, Haibing, Zhang, Laxi, Li, Huawen, Luo, Aiyue, Zhang, Dongwei, Wang, Yifei, Wang, Shixuan, Zhang, Zhefan, Zhang, Hongyu, Huang, Xiaodong, Yao, Paul, Ding, Yuanling, Liu, Zhengxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398526/
https://www.ncbi.nlm.nih.gov/pubmed/27470296
http://dx.doi.org/10.1111/acel.12515

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