Path‐seq identifies an essential mycolate remodeling program for mycobacterial host adaptation

The success of Mycobacterium tuberculosis (MTB) stems from its ability to remain hidden from the immune system within macrophages. Here, we report a new technology (Path‐seq) to sequence miniscule amounts of MTB transcripts within up to million‐fold excess host RNA. Using Path‐seq and regulatory net...

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Detalles Bibliográficos
Autores principales: Peterson, Eliza JR, Bailo, Rebeca, Rothchild, Alissa C, Arrieta‐Ortiz, Mario L, Kaur, Amardeep, Pan, Min, Mai, Dat, Abidi, Abrar A, Cooper, Charlotte, Aderem, Alan, Bhatt, Apoorva, Baliga, Nitin S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398593/
https://www.ncbi.nlm.nih.gov/pubmed/30833303
http://dx.doi.org/10.15252/msb.20188584

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