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Bazedoxifene exhibits growth suppressive activity by targeting interleukin‐6/glycoprotein 130/signal transducer and activator of transcription 3 signaling in hepatocellular carcinoma

The interleukin (IL)‐6/glycoprotein (GP)130/signal transducer and activator of transcription (STAT)3 pathway is emerging as a target for the treatment of hepatocellular carcinoma. IL‐6 binds to IL‐6R, forming a binary complex, which further combines with GP130 to transduce extracellular signaling by...

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Detalles Bibliográficos
Autores principales: Ma, Haiyan, Yan, Dan, Wang, Yina, Shi, Wei, Liu, Tianshu, Zhao, Chongqiang, Huo, Shengqi, Duan, Jialin, Tao, Jingwen, Zhai, Maocai, Luo, Pengcheng, Guo, Junyi, Tian, Lei, Mageta, Lulu, Jou, David, Zhang, Cuntai, Li, Chenglong, Lin, Jiayuh, Lv, Jiagao, Li, Sheng, Lin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398888/
https://www.ncbi.nlm.nih.gov/pubmed/30648776
http://dx.doi.org/10.1111/cas.13940