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PIK3CD induces cell growth and invasion by activating AKT/GSK‐3β/β‐catenin signaling in colorectal cancer

The catalytic subunit p110δ of phosphoinositide 3‐kinase (PI3K) encoded by PIK3CD has been implicated in some human solid tumors. However, its roles in colorectal cancer (CRC) remain largely unknown. Here we found that PIK3CD was overexpressed in colon cancer tissues and CRC cell lines and was an in...

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Detalles Bibliográficos
Autores principales: Chen, Jing‐Song, Huang, Jiong‐Qiang, Luo, Bing, Dong, Shi‐Hao, Wang, Rong‐Chang, Jiang, Ze‐kun, Xie, Ying‐Kang, Yi, Wei, Wen, Guang‐Ming, Zhong, Jian‐Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398891/
https://www.ncbi.nlm.nih.gov/pubmed/30618098
http://dx.doi.org/10.1111/cas.13931

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