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Isolation of a Complex Formed Between Acinetobacter baumannii HemA and HemL, Key Enzymes of Tetrapyrroles Biosynthesis

Plants, algae and most bacteria synthesize 5-aminolevulinic acid (ALA), the universal precursor of tetrapyrroles such as heme, chlorophyll and coenzyme B(12), by a two-step transformation involving the NADPH-dependent glutamyl-tRNA reductase (HemA), which reduces tRNA-bound glutamate to glutamate-1-...

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Detalles Bibliográficos
Autores principales: Nardella, Caterina, Boi, Dalila, di Salvo, Martino L., Barile, Anna, Stetefeld, Jörg, Tramonti, Angela, Contestabile, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399207/
https://www.ncbi.nlm.nih.gov/pubmed/30863751
http://dx.doi.org/10.3389/fmolb.2019.00006

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