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High-resolution structure determination of sub-100 kDa complexes using conventional cryo-EM
Determining high-resolution structures of biological macromolecules amassing less than 100 kilodaltons (kDa) has been a longstanding goal of the cryo-electron microscopy (cryo-EM) community. While the Volta phase plate has enabled visualization of specimens in this size range, this instrumentation i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399227/ https://www.ncbi.nlm.nih.gov/pubmed/30833564 http://dx.doi.org/10.1038/s41467-019-08991-8 |