Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function

Inherited hearing loss is associated with gene mutations that result in sensory hair cell (HC) malfunction. HC structure is defined by the cytoskeleton, which is mainly composed of actin filaments and actin-binding partners. LIM motif-containing protein kinases (LIMKs) are the primary regulators of...

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Detalles Bibliográficos
Autores principales: Fang, Qiaojun, Zhang, Yuhua, Da, Peng, Shao, Buwei, Pan, Haolai, He, Zuhong, Cheng, Cheng, Li, Dan, Guo, Jiaqi, Wu, Xiaohan, Guan, Ming, Liao, Menghui, Zhang, Yuan, Sha, Suhua, Zhou, Zikai, Wang, Jian, Wang, Tian, Su, Kaiming, Chai, Renjie, Chen, Fangyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399249/
https://www.ncbi.nlm.nih.gov/pubmed/30833597
http://dx.doi.org/10.1038/s41598-019-39769-z

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