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p300/CBP-associated factor promotes autophagic degradation of δ-catenin through acetylation and decreases prostate cancer tumorigenicity
δ-Catenin shares common binding partners with β-catenin. As acetylation and deacetylation regulate β-catenin stability, we searched for histone acetyltransferases (HATs) or histone deacetylases (HDACs) affecting δ-catenin acetylation status and protein levels. We showed that p300/CBP-associated fact...
Autores principales: | Zhou, Rui, Yang, Yi, Park, So-Yeon, Seo, Young-Woo, Jung, Sang-Chul, Kim, Kyung Keun, Kim, Kwonseop, Kim, Hangun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399259/ https://www.ncbi.nlm.nih.gov/pubmed/30833716 http://dx.doi.org/10.1038/s41598-019-40238-w |
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