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Direct imaging of the recruitment and phosphorylation of S6K1 in the mTORC1 pathway in living cells
Knowledge of protein signalling pathways in the working cell is seen as a primary route to identifying and developing targeted medicines. In recent years there has been a growing awareness of the importance of the mTOR pathway, making it an attractive target for therapeutic intervention in several d...
Autores principales: | Ahmed, Abdullah R., Owens, Raymond J., Stubbs, Christopher D., Parker, Anthony W., Hitchman, Richard, Yadav, Rahul B., Dumoux, Maud, Hawes, Chris, Botchway, Stanley W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399282/ https://www.ncbi.nlm.nih.gov/pubmed/30833605 http://dx.doi.org/10.1038/s41598-019-39410-z |
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