Dysfunctional high-density lipoprotein activates toll-like receptors via serum amyloid A in vascular smooth muscle cells

Serum amyloid A (SAA) is an uremic toxin and acute phase protein. It accumulates under inflammatory conditions associated with high cardiovascular morbidity and mortality in patients with sepsis or end-stage renal disease (ESRD). SAA is an apolipoprotein of the high-density lipoprotein (HDL). SAA ac...

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Detalles Bibliográficos
Autores principales: Schuchardt, Mirjam, Prüfer, Nicole, Tu, Yuexing, Herrmann, Jaqueline, Hu, Xiu-Ping, Chebli, Sarah, Dahlke, Katja, Zidek, Walter, van der Giet, Markus, Tölle, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399289/
https://www.ncbi.nlm.nih.gov/pubmed/30833653
http://dx.doi.org/10.1038/s41598-019-39846-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399289/
https://www.ncbi.nlm.nih.gov/pubmed/30833653
http://dx.doi.org/10.1038/s41598-019-39846-3

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