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GM-CSF Promotes the Expansion and Differentiation of Cord Blood Myeloid-Derived Suppressor Cells, Which Attenuate Xenogeneic Graft-vs.-Host Disease

Myeloid-derived suppressor cells (MDSCs) are increased in tumor patients. Studies have shown generation of MDSCs from human peripheral blood mononuclear cells (PBMCs) by various cytokine combinations. However, large scale expansion of human MDSCs has not been demonstrated or applied in clinic settin...

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Detalles Bibliográficos
Autores principales: Park, Mi-Young, Lim, Bang-Geul, Kim, Su-Yeon, Sohn, Hyun-Jung, Kim, Sueon, Kim, Tai-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399310/
https://www.ncbi.nlm.nih.gov/pubmed/30863394
http://dx.doi.org/10.3389/fimmu.2019.00183