Cargando…
GM-CSF Promotes the Expansion and Differentiation of Cord Blood Myeloid-Derived Suppressor Cells, Which Attenuate Xenogeneic Graft-vs.-Host Disease
Myeloid-derived suppressor cells (MDSCs) are increased in tumor patients. Studies have shown generation of MDSCs from human peripheral blood mononuclear cells (PBMCs) by various cytokine combinations. However, large scale expansion of human MDSCs has not been demonstrated or applied in clinic settin...
Autores principales: | Park, Mi-Young, Lim, Bang-Geul, Kim, Su-Yeon, Sohn, Hyun-Jung, Kim, Sueon, Kim, Tai-Gyu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399310/ https://www.ncbi.nlm.nih.gov/pubmed/30863394 http://dx.doi.org/10.3389/fimmu.2019.00183 |
Ejemplares similares
-
Local Myeloid-Derived Suppressor Cells Impair Progression of Experimental Autoimmune Uveitis by Alleviating Oxidative Stress and Inflammation
por: Lee, Jae-Young, et al.
Publicado: (2023) -
GM-CSF Nitration Is a New Driver of Myeloid Suppressor Cell Activity in Tumors
por: Calì, Bianca, et al.
Publicado: (2021) -
Local and Systemic Injections of Human Cord Blood Myeloid-Derived Suppressor Cells to Prevent Graft Rejection in Corneal Transplantation
por: Lee, Jae-young, et al.
Publicado: (2022) -
GM-CSF Quantity Has a Selective Effect on Granulocytic vs. Monocytic Myeloid Development and Function
por: Sun, Li, et al.
Publicado: (2018) -
GM-CSF signalling blockade and chemotherapeutic agents act in concert to inhibit the function of myeloid-derived suppressor cells in vitro
por: Gargett, Tessa, et al.
Publicado: (2016)