The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression

The interactions between tumor cells with their microenvironments, including hypoxia, acidosis and immune cells, lead to the tumor heterogeneity which promotes tumor progression. Here, we show that SIAH2-NRF1 axis remodels tumor microenvironment through regulating tumor mitochondrial function, tumor...

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Detalles Bibliográficos
Autores principales: Ma, Biao, Cheng, Hongcheng, Mu, Chenglong, Geng, Guangfeng, Zhao, Tian, Luo, Qian, Ma, Kaili, Chang, Rui, Liu, Qiangqiang, Gao, Ruize, Nie, Junli, Xie, Jiaying, Han, Jinxue, Chen, Linbo, Ma, Gui, Zhu, Yushan, Chen, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399320/
https://www.ncbi.nlm.nih.gov/pubmed/30833558
http://dx.doi.org/10.1038/s41467-019-08618-y

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