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Neuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediated process
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by synaptic loss that leads to the development of cognitive deficits. Synapses are neuronal structures that play a crucial role in memory formation and are known to consume most of the energy used in the brain. Interestingly, AMP...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399353/ https://www.ncbi.nlm.nih.gov/pubmed/30833547 http://dx.doi.org/10.1038/s41419-019-1464-x |