How clinical imaging can assess cancer biology

Human cancers represent complex structures, which display substantial inter- and intratumor heterogeneity in their genetic expression and phenotypic features. However, cancers usually exhibit characteristic structural, physiologic, and molecular features and display specific biological capabilities...

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Detalles Bibliográficos
Autores principales: García-Figueiras, Roberto, Baleato-González, Sandra, Padhani, Anwar R., Luna-Alcalá, Antonio, Vallejo-Casas, Juan Antonio, Sala, Evis, Vilanova, Joan C., Koh, Dow-Mu, Herranz-Carnero, Michel, Vargas, Herbert Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399375/
https://www.ncbi.nlm.nih.gov/pubmed/30830470
http://dx.doi.org/10.1186/s13244-019-0703-0
Descripción
Sumario:Human cancers represent complex structures, which display substantial inter- and intratumor heterogeneity in their genetic expression and phenotypic features. However, cancers usually exhibit characteristic structural, physiologic, and molecular features and display specific biological capabilities named hallmarks. Many of these tumor traits are imageable through different imaging techniques. Imaging is able to spatially map key cancer features and tumor heterogeneity improving tumor diagnosis, characterization, and management. This paper aims to summarize the current and emerging applications of imaging in tumor biology assessment. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13244-019-0703-0) contains supplementary material, which is available to authorized users.

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