Sleep-State Dependent Alterations in Brain Functional Connectivity under Urethane Anesthesia in a Rat Model of Early-Stage Parkinson’s Disease

Parkinson’s disease (PD) is characterized by the gradual degeneration of dopaminergic neurons in the substantia nigra, leading to striatal dopamine depletion. A partial unilateral striatal 6-hydroxydopamine (6-OHDA) lesion causes 40–60% dopamine depletion in the lesioned rat striatum, modeling the e...

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Detalles Bibliográficos
Autores principales: Zhurakovskaya, Ekaterina, Leikas, Juuso, Pirttimäki, Tiina, Casas Mon, Francesc, Gynther, Mikko, Aliev, Rubin, Rantamäki, Tomi, Tanila, Heikki, Forsberg, Markus M., Gröhn, Olli, Paasonen, Jaakko, Jalkanen, Aaro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399428/
https://www.ncbi.nlm.nih.gov/pubmed/30838323
http://dx.doi.org/10.1523/ENEURO.0456-18.2019

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