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Herpes Simplex Virus Type 2 Immediate Early Protein ICP27 Inhibits IFN-β Production in Mucosal Epithelial Cells by Antagonizing IRF3 Activation

Herpes simplex virus type 2 (HSV-2) is the main cause of genital herpes and infections are common in the lower genital tract. Although neuronal and immune cells can be infected, epithelial cells, and keratinocytes are the primary HSV-2 target cells. HSV-2 establishes latency by evading the host immu...

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Detalles Bibliográficos
Autores principales:	Guan, Xinmeng, Zhang, Mudan, Fu, Ming, Luo, Sukun, Hu, Qinxue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399465/ https://www.ncbi.nlm.nih.gov/pubmed/30863402 http://dx.doi.org/10.3389/fimmu.2019.00290

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