Cargando…

MSP-RON Signaling Is Activated in the Transition From Pancreatic Intraepithelial Neoplasia (PanIN) to Pancreatic Ductal Adenocarcinoma (PDAC)

Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest epithelial malignancies and remains difficult to treat. Pancreatic intraepithelial neoplasias (PanINs) represent the majority of the pre-cancer lesions in the pancreas. The PDAC microenvironment consists of activated pancreatic stellate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Ce, Morvaridi, Susan, Lam, Gloria, Chheda, Chintan, Kamata, Yoshiko, Katsumata, Makoto, Edderkaoui, Mouad, Yuan, Xiaopu, Nissen, Nicholas, Pandol, Stephen J., Wang, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399467/ https://www.ncbi.nlm.nih.gov/pubmed/30863319 http://dx.doi.org/10.3389/fphys.2019.00147

Ejemplares similares

Expression of Chosen Carcinoembryonic-Related Cell Adhesion Molecules in Pancreatic Intraepithelial Neoplasia (PanIN) Associated with Chronic Pancreatitis and Pancreatic Ductal Adenocarcinoma (PDAC)
por: Zińczuk, Justyna, et al.
Publicado: (2019)

Acinar-to-Ductal Metaplasia (ADM): On the Road to Pancreatic Intraepithelial Neoplasia (PanIN) and Pancreatic Cancer
por: Marstrand-Daucé, Louis, et al.
Publicado: (2023)

HDAC3 mediates smoking-induced pancreatic cancer
por: Edderkaoui, Mouad, et al.
Publicado: (2016)

What are the macrophages and stellate cells doing in pancreatic adenocarcinoma?
por: Pandol, Stephen J., et al.
Publicado: (2015)

Periampullary localized pancreatic intraepithelial neoplasia-3 (PanIN-3): evaluation with contrast-enhanced MR cholangiography (MRCP)
por: Algin, Oktay, et al.
Publicado: (2011)

The Potential for Circulating Tumor Cells in Pancreatic Cancer Management
por: Pimienta, Michael, et al.
Publicado: (2017)

Survival Outcomes of Pancreatic Intraepithelial Neoplasm (PanIN) versus Intraductal Papillary Mucinous Neoplasm (IPMN) Associated Pancreatic Adenocarcinoma
por: McGinnis, Timothy, et al.
Publicado: (2020)

Glycogen Synthase Kinase 3β: A True Foe in Pancreatic Cancer
por: Elmadbouh, Omer H. M., et al.
Publicado: (2022)

Early Detection of Pancreatic Intraepithelial Neoplasias (PanINs) in Transgenic Mouse Model by Hyperpolarized (13)C Metabolic Magnetic Resonance Spectroscopy
por: Dutta, Prasanta, et al.
Publicado: (2020)

Metachronous pancreatic cancer originating from disseminated founder pancreatic intraductal neoplasias (PanINs)
por: Imai, Koji, et al.
Publicado: (2015)

Smoking and Pancreatic Disease
por: Edderkaoui, Mouad, et al.
Publicado: (2013)

Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN
por: Distler, M., et al.
Publicado: (2014)

Risk factors for pancreatic cancer: underlying mechanisms and potential targets
por: Edderkaoui, Mouad, et al.
Publicado: (2014)

MSP-RON Pathway: Potential Regulator of Inflammation and Innate Immunity
por: Huang, Lingtong, et al.
Publicado: (2020)

Histological Characterization of Biliary Intraepithelial Neoplasia with respect to Pancreatic Intraepithelial Neoplasia
por: Sato, Yasunori, et al.
Publicado: (2014)

Tumor Microenvironment in Pancreatic Intraepithelial Neoplasia
por: Opitz, Friederike V., et al.
Publicado: (2021)

Protective effects of urocortin 2 against caerulein-induced acute pancreatitis
por: Yuan, Jingzhen, et al.
Publicado: (2019)

Expression of SNAIL in accompanying PanIN is a key prognostic indicator in pancreatic ductal adenocarcinomas
por: Fujiwara, Sho, et al.
Publicado: (2019)

Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis
por: Morvaridi, Susan, et al.
Publicado: (2015)

BLT2 is expressed in PanINs, IPMNs, pancreatic cancer and stimulates tumour cell proliferation
por: Hennig, R, et al.
Publicado: (2008)

Branch Duct – IPMN and PanIN, in IgG4‐Autoimmune pancreatitis: A case report
por: Lazzarin, Gianni, et al.
Publicado: (2020)

Novel Small Molecule Inhibitors of Protein Kinase D Suppress NF-kappaB Activation and Attenuate the Severity of Rat Cerulein Pancreatitis
por: Yuan, Jingzhen, et al.
Publicado: (2017)

Determination of Rottlerin, a Natural Protein Kinases C Inhibitor, in Pancreatic Cancer Cells and Mouse Xenografts by RP-HPLC Method
por: Lu, Qing-Yi, et al.
Publicado: (2012)

Sequestration of Intestinal Acidic Toxins by Cationic Resin Attenuates Pancreatic Cancer Progression through Promoting Autophagic Flux for YAP Degradation
por: Zhao, Guangfu, et al.
Publicado: (2022)

Microinvasion of High-Grade Pancreatic Intraepithelial Neoplasia
por: Kawada, Natsuko, et al.
Publicado: (2013)

Clinical significance of pancreatic intraepithelial neoplasia in resectable pancreatic cancer on survivals
por: Yu, Da-Young, et al.
Publicado: (2018)

Overexpression of Mesothelin in Pancreatic Ductal Adenocarcinoma (PDAC)
por: Le, Kai, et al.
Publicado: (2020)

Ron Knockdown and Ron Monoclonal Antibody IMC-RON8 Sensitize Pancreatic Cancer to Histone Deacetylase Inhibitors (HDACi)
por: Zou, Yi, et al.
Publicado: (2013)

Smad4 Loss Synergizes with TGFα Overexpression in Promoting Pancreatic Metaplasia, PanIN Development, and Fibrosis
por: Garcia-Carracedo, Dario, et al.
Publicado: (2015)

Presence of pancreatic intraepithelial neoplasia-3 in a background of chronic pancreatitis in pancreatic cancer patients
por: Hwang, In Kyeom, et al.
Publicado: (2015)

Modifiable Pancreatic Ductal Adenocarcinoma (PDAC) Risk Factors
por: Michalak, Natalia, et al.
Publicado: (2023)

The role of survivin in the progression of pancreatic ductal adenocarcinoma (PDAC) and a novel survivin-targeted therapeutic for PDAC
por: Brown, Matthew, et al.
Publicado: (2020)

Integrating Gemcitabine-Based Therapy With AdipoRon Enhances Growth Inhibition in Human PDAC Cell Lines
por: Ragone, Angela, et al.
Publicado: (2022)

RON is not a prognostic marker for resectable pancreatic cancer
por: Tactacan, Carole M, et al.
Publicado: (2012)

The MSP‐RON axis stimulates cancer cell growth in models of triple negative breast cancer
por: Millar, Rhona, et al.
Publicado: (2020)

A Case of Pancreatic Intraepithelial Neoplasia That Was Difficult to Diagnose Preoperatively
por: Ito, Hiroyuki, et al.
Publicado: (2015)

Identification of KIAA1199 as a Biomarker for Pancreatic Intraepithelial Neoplasia
por: Suh, Han Na, et al.
Publicado: (2016)

MicroRNAs as Indicators of Malignancy in Pancreatic Ductal Adenocarcinoma (PDAC) and Cystic Pancreatic Lesions
por: Prinz, Christian, et al.
Publicado: (2022)

SIRT 1 Overexpression is Associated with Metastasis of Pancreatic Ductal Adenocarcinoma (PDAC) and Promotes Migration and Growth of PDAC Cells
por: Li, Siqin, et al.
Publicado: (2016)

Integration of metabolites from meta-analysis with transcriptome reveals enhanced SPHK1 in PDAC with a background of pancreatitis
por: Ketavarapu, Vijayasarathy, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9s3psou4qvqgbd6t2qdkva0jb1