Cargando…

Metformin Promotes Neuronal Differentiation via Crosstalk between Cdk5 and Sox6 in Neuroblastoma Cells

Metformin has recently emerged as a key player in promotion of neuroblastoma differentiation and neurite outgrowth. However, molecular mechanisms of how metformin promotes cellular differentiation have not yet been fully elucidated. In this study, we investigated how metformin promotes cell differen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Binlateh, Thunwa, Tanasawet, Supita, Rattanaporn, Onnicha, Sukketsiri, Wanida, Hutamekalin, Pilaiwanwadee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399528/ https://www.ncbi.nlm.nih.gov/pubmed/30911317 http://dx.doi.org/10.1155/2019/1765182

Ejemplares similares

Metformin Inhibit Cervical Cancer Migration by Suppressing the FAK/Akt Signaling Pathway
por: Hakimee, Henna, et al.
Publicado: (2019)

Luteolin attenuates migration and invasion of lung cancer cells via suppressing focal adhesion kinase and non-receptor tyrosine kinase signaling pathway
por: Masraksa, Wuttipong, et al.
Publicado: (2020)

In vitro antioxidant and wound-healing activities of hydrolyzed collagen from defatted Asian sea bass skin as influenced by different enzyme types and hydrolysis processes
por: Chotphruethipong, Lalita, et al.
Publicado: (2021)

Astaxanthin induces migration in human skin keratinocytes via Rac1 activation and RhoA inhibition
por: Ritto, Dakanda, et al.
Publicado: (2017)

Suppressing Cdk5 Activity by Luteolin Inhibits MPP(+)-Induced Apoptotic of Neuroblastoma through Erk/Drp1 and Fak/Akt/GSK3β Pathways
por: Reudhabibadh, Ratchaneekorn, et al.
Publicado: (2021)

Antimetastatic effect of fucoidan against non-small cell lung cancer by suppressing non-receptor tyrosine kinase and extracellular signal-related kinase pathway
por: Muneerungsee, Nareenath, et al.
Publicado: (2023)

Impact of Hydrolyzed Collagen from Defatted Sea Bass Skin on Proliferation and Differentiation of Preosteoblast MC3T3-E1 Cells
por: Chotphruethipong, Lalita, et al.
Publicado: (2021)

Effects of Apium graveolens Extract on the Oxidative Stress in the Liver of Adjuvant-Induced Arthritic Rats
por: Sukketsiri, Wanida, et al.
Publicado: (2016)

Cordycepin attenuates migration and invasion of HSC-4 oral squamous carcinoma cells through autophagy-dependent FAK/Akt and MMP2/MMP9 suppression
por: Binlateh, Thunwa, et al.
Publicado: (2022)

The antioxidant and neurochemical activity of Apium graveolens L. and its ameliorative effect on MPTP-induced Parkinson-like symptoms in mice
por: Chonpathompikunlert, Pennapa, et al.
Publicado: (2018)

Collagen-Based Biomaterials in Periodontal Regeneration: Current Applications and Future Perspectives of Plant-Based Collagen
por: Binlateh, Thunwa, et al.
Publicado: (2022)

Arthrogenicity of type II collagen monoclonal antibodies associated with complement activation and antigen affinity
por: Koobkokkruad, Thongchai, et al.
Publicado: (2011)

SOX4 Mediates ATRA-Induced Differentiation in Neuroblastoma Cells
por: Zhang, Dongyang, et al.
Publicado: (2022)

Missing and overexpressing proteins in domestic cat oocytes following vitrification and in vitro maturation as revealed by proteomic analysis
por: Turathum, Bongkoch, et al.
Publicado: (2018)

Human paraoxonase 2
por: Porntadavity, Sureerut, et al.
Publicado: (2010)

Effects of Astaxanthin from Shrimp Shell on Oxidative Stress and Behavior in Animal Model of Alzheimer’s Disease
por: Taksima, Takunrat, et al.
Publicado: (2019)

Chitooligosaccharide from Pacific White Shrimp Shell Chitosan Ameliorates Inflammation and Oxidative Stress via NF-κB, Erk1/2, Akt and Nrf2/HO-1 Pathways in LPS-Induced RAW264.7 Macrophage Cells
por: Chotphruethipong, Lalita, et al.
Publicado: (2023)

Conjugate between hydrolyzed collagen from defatted seabass skin and epigallocatechin gallate (EGCG): characteristics, antioxidant activity and in vitro cellular bioactivity
por: Chotphruethipong, Lalita, et al.
Publicado: (2021)

CDK4/6 and MAPK—Crosstalk as Opportunity for Cancer Treatment
por: Scheiblecker, Lisa, et al.
Publicado: (2020)

Chitooligosaccharide prevents vascular endothelial cell apoptosis by attenuation of endoplasmic reticulum stress via suppression of oxidative stress through Nrf2-SOD1 up-regulation
por: Ei, Zin Zin, et al.
Publicado: (2022)

Inhibition of CDK4/6 as a novel therapeutic option for neuroblastoma
por: Rihani, Ali, et al.
Publicado: (2015)

Multiple CDK inhibitor dinaciclib suppresses neuroblastoma growth via inhibiting CDK2 and CDK9 activity
por: Chen, Zhenghu, et al.
Publicado: (2016)

Oral Administration of Ethanolic Extract of Shrimp Shells-Loaded Liposome Protects against Aβ-Induced Memory Impairment in Rats
por: Kuedo, Zulkiflee, et al.
Publicado: (2022)

SOX2 Regulates Neuronal Differentiation of the Suprachiasmatic Nucleus
por: Cheng, Arthur H., et al.
Publicado: (2021)

Crosstalk between SOX2 and cytokine signaling in endometrial carcinoma
por: Lee, Chang-Jung, et al.
Publicado: (2018)

Time-Dependent Pathological Changes in Hypoperfusion-Induced Abdominal Aortic Aneurysm
por: Kugo, Hirona, et al.
Publicado: (2021)

Low glucose and serum levels cause an increased inflammatory factor in 3T3-L1 cell through Akt, MAPKs and NF-кB activation
por: Kugo, Hirona, et al.
Publicado: (2021)

Crosstalk between SOX Genes and Long Non-Coding RNAs in Glioblastoma
por: Stevanovic, Milena, et al.
Publicado: (2023)

Metformin acts in the gut and induces gut-liver crosstalk
por: Tobar, Natália, et al.
Publicado: (2023)

Mesenchymal Stromal Cells in Neuroblastoma: Exploring Crosstalk and Therapeutic Implications
por: Hochheuser, Caroline, et al.
Publicado: (2021)

Editorial: Neuroblastoma: Signal Crosstalk and Future Insight Into Clinical Trials
por: Ando, Kiyohiro, et al.
Publicado: (2022)

Proteomic investigation of Cbl and Cbl-b in neuroblastoma cell differentiation highlights roles for SHP-2 and CDK16
por: Pedersen, Anna-Kathrine, et al.
Publicado: (2021)

Sox9 is involved in the thyroid differentiation program and is regulated by crosstalk between TSH, TGFβ and thyroid transcription factors
por: López-Márquez, Arístides, et al.
Publicado: (2022)

Crosstalk between BMP and Notch Induces Sox2 in Cerebral Endothelial Cells
por: Wu, Xiuju, et al.
Publicado: (2019)

A state of stochastic cancer stemness through the CDK1-SOX2 axis
por: Menon, Dinoop Ravindran, et al.
Publicado: (2019)

Crosstalk between Cdk5 and GSK3β: Implications for Alzheimer's Disease
por: Engmann, Olivia, et al.
Publicado: (2009)

Colitis promotes neuronal differentiation of Sox2+ and PLP1+ enteric cells
por: Belkind-Gerson, Jaime, et al.
Publicado: (2017)

LINC01296 promotes neuroblastoma tumorigenesis via the NCL-SOX11 regulatory complex
por: Wang, Jing, et al.
Publicado: (2022)

Retinoic acid-induced CHD5 upregulation and neuronal differentiation of neuroblastoma
por: Higashi, Mayumi, et al.
Publicado: (2015)

ZNF281 inhibits neuronal differentiation and is a prognostic marker for neuroblastoma
por: Pieraccioli, Marco, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qdjo461i4cllj920ahqbvlm7ku