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Efficient Therapeutic Function and Mechanisms of Human Polyclonal CD8(+)CD103(+)Foxp3(+) Regulatory T Cells on Collagen-Induced Arthritis in Mice

OBJECTIVE: To investigate the potential therapeutic effect in a rheumatoid arthritis model of stable human CD8(+) regulatory T cells (hCD8(+)Tregs) induced by TGF-β1 and rapamycin (RAPA) in vitro. METHODS: Human CD8(+)T cells were isolated from human peripheral blood mononuclear cells and induced/ex...

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Autores principales:	Sun, Juan, Yang, Yiming, Huo, Xiaona, Zhu, Beibei, Li, Zhenhua, Jiang, Xueyu, Xie, Rufeng, Gao, Li, Sun, Ying, Fan, Huahua, Zhu, Yongming, Yang, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399536/ https://www.ncbi.nlm.nih.gov/pubmed/30915372 http://dx.doi.org/10.1155/2019/8575407

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