Likelihood-Ratio-Test Methods for Drug Safety Signal Detection from Multiple Clinical Datasets

Pre- and postmarket drug safety evaluations usually include an integrated summary of results obtained using data from multiple studies related to a drug of interest. This paper proposes three approaches based on the likelihood ratio test (LRT), called the LRT methods, for drug safety signal detectio...

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Detalles Bibliográficos
Autores principales: Huang, Lan, Zalkikar, Jyoti, Tiwari, Ram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399568/
https://www.ncbi.nlm.nih.gov/pubmed/30915153
http://dx.doi.org/10.1155/2019/1526290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399568/
https://www.ncbi.nlm.nih.gov/pubmed/30915153
http://dx.doi.org/10.1155/2019/1526290

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