The lysine‐specific methyltransferase KMT2C/MLL3 regulates DNA repair components in cancer

Genome‐wide studies in tumor cells have indicated that chromatin‐modifying proteins are commonly mutated in human cancers. The lysine‐specific methyltransferase 2C (KMT2C/MLL3) is a putative tumor suppressor in several epithelia and in myeloid cells. Here, we show that downregulation of KMT2C in bla...

Descripción completa

Detalles Bibliográficos
Autores principales: Rampias, Theodoros, Karagiannis, Dimitris, Avgeris, Margaritis, Polyzos, Alexander, Kokkalis, Antonis, Kanaki, Zoi, Kousidou, Evgenia, Tzetis, Maria, Kanavakis, Emmanouil, Stravodimos, Konstantinos, Manola, Kalliopi N, Pantelias, Gabriel E, Scorilas, Andreas, Klinakis, Apostolos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399616/
https://www.ncbi.nlm.nih.gov/pubmed/30665945
http://dx.doi.org/10.15252/embr.201846821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399616/
https://www.ncbi.nlm.nih.gov/pubmed/30665945
http://dx.doi.org/10.15252/embr.201846821

Ejemplares similares