Exceptional response and multisystem autoimmune-like toxicities associated with the same T cell clone in a patient with uveal melanoma treated with immune checkpoint inhibitors

Balancing the potential for durable remissions with autoimmune-like toxicities is a key clinical challenge in the use of immune checkpoint inhibitors (ICI). Certain toxicities are associated with an increased response rate; however, the molecular underpinnings of this association are poorly understo...

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Detalles Bibliográficos
Autores principales: Rapisuwon, Suthee, Izar, Benjamin, Batenchuk, Cory, Avila, Alexandre, Mei, Shaolin, Sorger, Peter, Parks, Jerry M., Cooper, Sarah J., Wagner, David, Zeck, Jay C., Charabaty, Aline J., Atkins, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399858/
https://www.ncbi.nlm.nih.gov/pubmed/30832716
http://dx.doi.org/10.1186/s40425-019-0533-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399858/
https://www.ncbi.nlm.nih.gov/pubmed/30832716
http://dx.doi.org/10.1186/s40425-019-0533-0

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