Personalized medicine with IgGAM compared with standard of care for treatment of peritonitis after infectious source control (the PEPPER trial): study protocol for a randomized controlled trial

BACKGROUND: Peritonitis is responsible for thousands of deaths annually in Germany alone. Even source control (SC) and antibiotic treatment often fail to prevent severe sepsis or septic shock, and this situation has hardly improved in the past two decades. Most experimental immunomodulatory therapeu...

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Detalles Bibliográficos
Autores principales: Kalvelage, Christina, Zacharowski, Kai, Bauhofer, Artur, Gockel, Ulrich, Adamzik, Michael, Nierhaus, Axel, Kujath, Peter, Eckmann, Christian, Pletz, Mathias W., Bracht, Hendrik, Simon, Tim-Philipp, Winkler, Michael, Kindgen-Milles, Detlef, Albertsmeier, Markus, Weigand, Markus, Ellger, Björn, Ragaller, Maximilian, Ullrich, Roman, Marx, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399861/
https://www.ncbi.nlm.nih.gov/pubmed/30832742
http://dx.doi.org/10.1186/s13063-019-3244-4

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