Human Interleukin-34 facilitates microglia-like cell differentiation and persistent HIV-1 infection in humanized mice

BACKGROUND: Microglia are the principal innate immune defense cells of the centeral nervous system (CNS) and the target of the human immunodeficiency virus type one (HIV-1). A complete understanding of human microglial biology and function requires the cell’s presence in a brain microenvironment. La...

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Detalles Bibliográficos
Autores principales: Mathews, Saumi, Branch Woods, Amanda, Katano, Ikumi, Makarov, Edward, Thomas, Midhun B., Gendelman, Howard E., Poluektova, Larisa Y., Ito, Mamoru, Gorantla, Santhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399898/
https://www.ncbi.nlm.nih.gov/pubmed/30832693
http://dx.doi.org/10.1186/s13024-019-0311-y

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