Activation of the kynurenine pathway is associated with poor outcome in Pneumocystis pneumonia patients infected with HIV: results of 2 months cohort study

BACKGROUND: Indoleamine 2, 3-dioxygenase (IDO) is a key enzyme in the degradation of tryptophan (Trp) to kynurenine (Kyn). We measured IDO activity as the Kyn to Trp ratio, and investigated whether IDO could be used to assess prognosis of acquired immune deficiency Sydrome (AIDS) patients with pneum...

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Detalles Bibliográficos
Autores principales: Wang, Mengyan, Dong, Xiaotian, Huang, Ying, Su, Junwei, Dai, Xiahong, Guo, Yongzheng, Hu, Caiqin, Zhou, Qihui, Zhu, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399927/
https://www.ncbi.nlm.nih.gov/pubmed/30832615
http://dx.doi.org/10.1186/s12879-019-3851-4

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