Downregulation of RNF128 activates Wnt/β-catenin signaling to induce cellular EMT and stemness via CD44 and CTTN ubiquitination in melanoma

BACKGROUND: Ring finger proteins (RNFs) were involved in carcinogenesis. Here, we aimed to explore the detailed mechanism of RNF128 in the progression of melanoma. METHODS: We reanalyzed several gene expression profiles from the Gene Expression Omnibus (GEO) database and obtained the overlapped diff...

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Detalles Bibliográficos
Autores principales: Wei, Chuan-Yuan, Zhu, Meng-Xuan, Yang, Yan-Wen, Zhang, Peng-Fei, Yang, Xuan, Peng, Rui, Gao, Chao, Lu, Jia-Cheng, Wang, Lu, Deng, Xin-Yi, Lu, Nan-Hang, Qi, Fa-Zhi, Gu, Jian-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399928/
https://www.ncbi.nlm.nih.gov/pubmed/30832692
http://dx.doi.org/10.1186/s13045-019-0711-z

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