Cargando…
Enriched gestation activates the IGF pathway to evoke embryo-adult benefits to prevent Alzheimer’s disease
BACKGROUND: Building brain reserves before dementia onset could represent a promising strategy to prevent Alzheimer’s disease (AD), while how to initiate early cognitive stimulation is unclear. Given that the immature brain is more sensitive to environmental stimuli and that brain dynamics decrease...
Autores principales: | Liu, Enjie, Zhou, Qiuzhi, Xie, Ao-Ji, Li, Mengzhu, Zhang, Shujuan, Huang, Hezhou, Liuyang, Zhenyu, Wang, Yali, Liu, Bingjin, Li, Xiaoguang, Sun, Dongsheng, Wei, Yuping, Wang, Xiaochuan, Wang, Qun, Ke, Dan, Yang, Xifei, Yang, Ying, Wang, Jian-Zhi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399936/ https://www.ncbi.nlm.nih.gov/pubmed/30867903 http://dx.doi.org/10.1186/s40035-019-0149-9 |
Ejemplares similares
-
GSK-3β deletion in dentate gyrus excitatory neuron impairs synaptic plasticity and memory
por: Liu, Enjie, et al.
Publicado: (2017) -
Peripheral inflammation promotes brain tau transmission via disrupting blood–brain barrier
por: Liu, Yanchao, et al.
Publicado: (2020) -
Human tau accumulation promotes glycogen synthase kinase-3β acetylation and thus upregulates the kinase: A vicious cycle in Alzheimer neurodegeneration
por: Zhou, Qiuzhi, et al.
Publicado: (2022) -
Paternal spatial training enhances offspring’s cognitive performance and synaptic plasticity in wild-type but not improve memory deficit in Alzheimer’s mice
por: Zhang, Shujuan, et al.
Publicado: (2017) -
Alzheimer‐like tau accumulation in dentate gyrus mossy cells induces spatial cognitive deficits by disrupting multiple memory‐related signaling and inhibiting local neural circuit
por: Li, Shihong, et al.
Publicado: (2022)