Cargando…

FAT4 regulates the EMT and autophagy in colorectal cancer cells in part via the PI3K-AKT signaling axis

BACKGROUND: FAT4 functions as a tumor suppressor, and previous findings have demonstrated that FAT4 can inhibit the epithelial-to-mesenchymal transition (EMT) and the proliferation of gastric cancer cells. However, few studies have investigated the role of FAT4 in the development of colorectal cance...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Ran, Xiao, Yuhong, Song, Yi, Yuan, Huiping, Luo, Jun, Xu, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399964/ https://www.ncbi.nlm.nih.gov/pubmed/30832706 http://dx.doi.org/10.1186/s13046-019-1043-0

Ejemplares similares

PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway
por: Ma, Zhan, et al.
Publicado: (2020)

ARFIP2 Regulates EMT and Autophagy in Hepatocellular Carcinoma in Part Through the PI3K/Akt Signalling Pathway
por: Huang, Kaida, et al.
Publicado: (2022)

AURKB activates EMT through PI3K/AKT signaling axis to promote ICC progression
por: Ma, Peng, et al.
Publicado: (2023)

CRTC2 promotes paclitaxel resistance by inducing autophagy in ovarian cancer in part via the PI3K-AKT signaling axis
por: Ou, Chaoyang, et al.
Publicado: (2023)

KLHL22 Regulates the EMT and Proliferation in Colorectal Cancer Cells in Part via the Wnt/β-Catenin Signaling Pathway
por: Song, Yi, et al.
Publicado: (2020)

A PLCB1–PI3K–AKT Signaling Axis Activates EMT to Promote Cholangiocarcinoma Progression
por: Liang, Shuhang, et al.
Publicado: (2021)

LACTB Regulates PIK3R3 to Promote Autophagy and Inhibit EMT and Proliferation Through the PI3K/AKT/mTOR Signaling Pathway in Colorectal Cancer
por: Xu, Wei, et al.
Publicado: (2020)

Decorin Suppresses Invasion and EMT Phenotype of Glioma by Inducing Autophagy via c-Met/Akt/mTOR Axis
por: Jia, Yanfei, et al.
Publicado: (2021)

MST4 negatively regulates the EMT, invasion and metastasis of HCC cells by inactivating PI3K/AKT/Snail1 axis
por: Dian, Mei-Juan, et al.
Publicado: (2021)

Compound Kushen injection inhibits EMT of gastric cancer cells via the PI3K/AKT pathway
por: Li, Luo, et al.
Publicado: (2022)

BTC as a Novel Biomarker Contributing to EMT via the PI3K-AKT Pathway in OSCC
por: Shen, Ting, et al.
Publicado: (2022)

MOR promotes epithelial-mesenchymal transition and proliferation via PI3K/AKT signaling pathway in human colorectal cancer: MOR promotes EMT and proliferation
por: Gao, Lingling, et al.
Publicado: (2022)

NQO1 drives glioblastoma cell aggressiveness through EMT induction via the PI3K/Akt/mTOR/Snail pathway
por: Zheng, Lan, et al.
Publicado: (2023)

Pingyangmycin Activates Oral Carcinoma Cell Autophagy via the Phosphorylation of the PI3K/AKT/mTOR Axis to Achieve the Purpose of Treating Oral Carcinoma
por: Xu, Wei, et al.
Publicado: (2022)

CPA4 Promotes EMT in Pancreatic Cancer via Stimulating PI3K-AKT-mTOR Signaling
por: Shao, Qingliang, et al.
Publicado: (2020)

Ubenimex induces autophagy inhibition and EMT suppression to overcome cisplatin resistance in GC cells by perturbing the CD13/EMP3/PI3K/AKT/NF-κB axis
por: Guo, Qie, et al.
Publicado: (2019)

Hydrodynamic stress stimulates growth of cell clusters via the ANXA1/PI3K/AKT axis in colorectal cancer
por: Hagihara, Takeshi, et al.
Publicado: (2019)

TRPC1 promotes the genesis and progression of colorectal cancer via activating CaM-mediated PI3K/AKT signaling axis
por: Sun, Yang, et al.
Publicado: (2021)

Knockdown of MMP-1 inhibits the progression of colorectal cancer by suppressing the PI3K/Akt/c-myc signaling pathway and EMT
por: Wang, Kai, et al.
Publicado: (2020)

TEAD4 functions as a prognostic biomarker and triggers EMT via PI3K/AKT pathway in bladder cancer
por: Chi, Ming, et al.
Publicado: (2022)

RNF7 promotes glioma growth via the PI3K/AKT signalling axis
por: Tang, Nan, et al.
Publicado: (2022)

Hyperhomocysteinemia potentiates megakaryocyte differentiation and thrombopoiesis via GH-PI3K-Akt axis
por: Lei, Wenjing, et al.
Publicado: (2023)

Ligustrazine protects against chronic hypertensive glaucoma in rats by inhibiting autophagy via the PI3K-Akt/mTOR pathway
por: Du, Hong-yan, et al.
Publicado: (2021)

SIX4 promotes metastasis via activation of the PI3K-AKT pathway in colorectal cancer
por: Li, Guodong, et al.
Publicado: (2017)

Gli1 promotes colorectal cancer metastasis in a Foxm1-dependent manner by activating EMT and PI3K-AKT signaling
por: Zhang, Chuan, et al.
Publicado: (2016)

EEF1D Promotes Glioma Proliferation, Migration, and Invasion through EMT and PI3K/Akt Pathway
por: Xie, Cheng, et al.
Publicado: (2020)

Tanshinone IIa Induces Autophagy and Apoptosis via PI3K/Akt/mTOR Axis in Acute Promyelocytic Leukemia NB4 Cells
por: Pan, Yiming, et al.
Publicado: (2021)

Itaconate attenuates autoimmune hepatitis via PI3K/AKT/mTOR pathway-mediated inhibition of dendritic cell maturation and autophagy
por: Zhang, Qiyu, et al.
Publicado: (2023)

Apatinib induces apoptosis and autophagy via the PI3K/AKT/mTOR and MAPK/ERK signaling pathways in neuroblastoma
por: Yu, Xiying, et al.
Publicado: (2020)

lncRNA MALAT1 Promotes EMT Process and Cisplatin Resistance of Oral Squamous Cell Carcinoma via PI3K/AKT/m-TOR Signal Pathway
por: Wang, Ran, et al.
Publicado: (2020)

GPX2 promotes EMT and metastasis in non‐small cell lung cancer by activating PI3K/AKT/mTOR/Snail signaling axis
por: Peng, Fang, et al.
Publicado: (2023)

Induction of apoptosis and autophagy via mitochondria- and PI3K/Akt/mTOR-mediated pathways by E. adenophorum in hepatocytes of saanen goat
por: He, Yajun, et al.
Publicado: (2016)

Celastrus orbiculatus extract triggers apoptosis and autophagy via PI3K/Akt/mTOR inhibition in human colorectal cancer cells
por: Yang, Lin, et al.
Publicado: (2016)

Novel PI3K/Akt/mTOR signaling inhibitor, W922, prevents colorectal cancer growth via the regulation of autophagy
por: Wang, Jin, et al.
Publicado: (2020)

MRPS16 facilitates tumor progression via the PI3K/AKT/Snail signaling axis
por: Wang, Zhen, et al.
Publicado: (2020)

The circEPSTI1/mir-942-5p/LTBP2 axis regulates the progression of OSCC in the background of OSF via EMT and the PI3K/Akt/mTOR pathway
por: Wang, Jie, et al.
Publicado: (2020)

VDR agonists down regulate PI3K/Akt/mTOR axis and trigger autophagy in Kaposi's sarcoma cells
por: Suares, Alejandra, et al.
Publicado: (2019)

Nonstructural protein 6 of porcine epidemic diarrhea virus induces autophagy to promote viral replication via the PI3K/Akt/mTOR axis
por: Lin, Huixing, et al.
Publicado: (2020)

AKAP12 ameliorates liver injury via targeting PI3K/AKT/PCSK6 pathway
por: Wu, Xuan, et al.
Publicado: (2022)

The Neurotrophic Function of Glucagon-Like Peptide-1 Promotes Human Neuroblastoma Differentiation via the PI3K-AKT Axis
por: Yang, Jenq-Lin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_im3pk0aad892ob2rnlqnred3ln