Polygenic Risk Score Analysis of Alzheimer’s Disease in Cases without APOE4 or APOE2 Alleles

The We and others have previously shown that polygenic risk score analysis (PRS) has considerable predictive utility for identifying those at high risk of developing Alzheimer’s disease (AD) with an area under the curve (AUC) of >0.8. However, by far the greatest determinant of this risk is the a...

Descripción completa

Detalles Bibliográficos
Autores principales: Escott-Price, V., Myers, A., Huentelman, M., Shoai, M., Hardy, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399990/
https://www.ncbi.nlm.nih.gov/pubmed/30569081
http://dx.doi.org/10.14283/jpad.2018.46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399990/
https://www.ncbi.nlm.nih.gov/pubmed/30569081
http://dx.doi.org/10.14283/jpad.2018.46

Ejemplares similares