Allergic Reaction to Intravenous Atropine in a Patient with Organophosphate Poisoning

Atropine is a drug of choice for muscarinic effects in organophosphate (OP) poisoning. Allergic reaction to atropine is rare. Here, we report a case of a 17-year-old male who was admitted with clinical manifestations of acute OP poisoning. After intravenous atropine injection, cutaneous signs of hyp...

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Detalles Bibliográficos
Autores principales: Samsamshariat, Shiva, Honarjoo, Navid, Gheshlaghi, Farzad, Dorvashy, Gholamali, Eizadi-Mood, Nastaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400035/
https://www.ncbi.nlm.nih.gov/pubmed/30911562
http://dx.doi.org/10.4103/jrpp.JRPP_18_83
Descripción
Sumario:Atropine is a drug of choice for muscarinic effects in organophosphate (OP) poisoning. Allergic reaction to atropine is rare. Here, we report a case of a 17-year-old male who was admitted with clinical manifestations of acute OP poisoning. After intravenous atropine injection, cutaneous signs of hypersensitivity including erythema and urticarial were observed on his body. Atropine injection was stopped, and antihistamines and hydrocortisone were administered. His condition was improved, and he discharged with a good condition after 2 days hospitalization. Adverse allergic reaction to atropine should be in mind when managing OP poisoning cases.

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