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Allergic Reaction to Intravenous Atropine in a Patient with Organophosphate Poisoning

Atropine is a drug of choice for muscarinic effects in organophosphate (OP) poisoning. Allergic reaction to atropine is rare. Here, we report a case of a 17-year-old male who was admitted with clinical manifestations of acute OP poisoning. After intravenous atropine injection, cutaneous signs of hyp...

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Autores principales: Samsamshariat, Shiva, Honarjoo, Navid, Gheshlaghi, Farzad, Dorvashy, Gholamali, Eizadi-Mood, Nastaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400035/
https://www.ncbi.nlm.nih.gov/pubmed/30911562
http://dx.doi.org/10.4103/jrpp.JRPP_18_83
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author Samsamshariat, Shiva
Honarjoo, Navid
Gheshlaghi, Farzad
Dorvashy, Gholamali
Eizadi-Mood, Nastaran
author_facet Samsamshariat, Shiva
Honarjoo, Navid
Gheshlaghi, Farzad
Dorvashy, Gholamali
Eizadi-Mood, Nastaran
author_sort Samsamshariat, Shiva
collection PubMed
description Atropine is a drug of choice for muscarinic effects in organophosphate (OP) poisoning. Allergic reaction to atropine is rare. Here, we report a case of a 17-year-old male who was admitted with clinical manifestations of acute OP poisoning. After intravenous atropine injection, cutaneous signs of hypersensitivity including erythema and urticarial were observed on his body. Atropine injection was stopped, and antihistamines and hydrocortisone were administered. His condition was improved, and he discharged with a good condition after 2 days hospitalization. Adverse allergic reaction to atropine should be in mind when managing OP poisoning cases.
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spelling pubmed-64000352019-03-25 Allergic Reaction to Intravenous Atropine in a Patient with Organophosphate Poisoning Samsamshariat, Shiva Honarjoo, Navid Gheshlaghi, Farzad Dorvashy, Gholamali Eizadi-Mood, Nastaran J Res Pharm Pract Case Report Atropine is a drug of choice for muscarinic effects in organophosphate (OP) poisoning. Allergic reaction to atropine is rare. Here, we report a case of a 17-year-old male who was admitted with clinical manifestations of acute OP poisoning. After intravenous atropine injection, cutaneous signs of hypersensitivity including erythema and urticarial were observed on his body. Atropine injection was stopped, and antihistamines and hydrocortisone were administered. His condition was improved, and he discharged with a good condition after 2 days hospitalization. Adverse allergic reaction to atropine should be in mind when managing OP poisoning cases. Medknow Publications & Media Pvt Ltd 2019 /pmc/articles/PMC6400035/ /pubmed/30911562 http://dx.doi.org/10.4103/jrpp.JRPP_18_83 Text en Copyright: © 2019 Journal of Research in Pharmacy Practice http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Samsamshariat, Shiva
Honarjoo, Navid
Gheshlaghi, Farzad
Dorvashy, Gholamali
Eizadi-Mood, Nastaran
Allergic Reaction to Intravenous Atropine in a Patient with Organophosphate Poisoning
title Allergic Reaction to Intravenous Atropine in a Patient with Organophosphate Poisoning
title_full Allergic Reaction to Intravenous Atropine in a Patient with Organophosphate Poisoning
title_fullStr Allergic Reaction to Intravenous Atropine in a Patient with Organophosphate Poisoning
title_full_unstemmed Allergic Reaction to Intravenous Atropine in a Patient with Organophosphate Poisoning
title_short Allergic Reaction to Intravenous Atropine in a Patient with Organophosphate Poisoning
title_sort allergic reaction to intravenous atropine in a patient with organophosphate poisoning
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400035/
https://www.ncbi.nlm.nih.gov/pubmed/30911562
http://dx.doi.org/10.4103/jrpp.JRPP_18_83
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