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REV-ERBα Regulates T(H)17 Cell Development and Autoimmunity

RORγt is well recognized as the lineage-defining transcription factor for T helper 17 (T(H)17) cell development. However, the cell-intrinsic mechanisms that negatively regulate T(H)17 cell development and autoimmunity remain poorly understood. Here, we demonstrate that the transcriptional repressor...

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Detalles Bibliográficos
Autores principales: Amir, Mohammed, Chaudhari, Sweena, Wang, Ran, Campbell, Sean, Mosure, Sarah A., Chopp, Laura B., Lu, Qun, Shang, Jinsai, Pelletier, Oliver B., He, Yuanjun, Doebelin, Christelle, Cameron, Michael D., Kojetin, Douglas J., Kamenecka, Theodore M., Solt, Laura A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400287/
https://www.ncbi.nlm.nih.gov/pubmed/30590045
http://dx.doi.org/10.1016/j.celrep.2018.11.101

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