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REV-ERBα Regulates T(H)17 Cell Development and Autoimmunity
RORγt is well recognized as the lineage-defining transcription factor for T helper 17 (T(H)17) cell development. However, the cell-intrinsic mechanisms that negatively regulate T(H)17 cell development and autoimmunity remain poorly understood. Here, we demonstrate that the transcriptional repressor...
Autores principales: | Amir, Mohammed, Chaudhari, Sweena, Wang, Ran, Campbell, Sean, Mosure, Sarah A., Chopp, Laura B., Lu, Qun, Shang, Jinsai, Pelletier, Oliver B., He, Yuanjun, Doebelin, Christelle, Cameron, Michael D., Kojetin, Douglas J., Kamenecka, Theodore M., Solt, Laura A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400287/ https://www.ncbi.nlm.nih.gov/pubmed/30590045 http://dx.doi.org/10.1016/j.celrep.2018.11.101 |
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