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In vitro and in silico multidimensional modeling of oncolytic tumor virotherapy dynamics

Tumor therapy with replication competent viruses is an exciting approach to cancer eradication where viruses are engineered to specifically infect, replicate, spread and kill tumor cells. The outcome of tumor virotherapy is complex due to the variable interactions between the cancer cell and virus p...

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Detalles Bibliográficos
Autores principales: Berg, David R., Offord, Chetan P., Kemler, Iris, Ennis, Matthew K., Chang, Lawrence, Paulik, George, Bajzer, Zeljko, Neuhauser, Claudia, Dingli, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400333/
https://www.ncbi.nlm.nih.gov/pubmed/30835721
http://dx.doi.org/10.1371/journal.pcbi.1006773