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In vitro and in silico multidimensional modeling of oncolytic tumor virotherapy dynamics
Tumor therapy with replication competent viruses is an exciting approach to cancer eradication where viruses are engineered to specifically infect, replicate, spread and kill tumor cells. The outcome of tumor virotherapy is complex due to the variable interactions between the cancer cell and virus p...
Autores principales: | Berg, David R., Offord, Chetan P., Kemler, Iris, Ennis, Matthew K., Chang, Lawrence, Paulik, George, Bajzer, Zeljko, Neuhauser, Claudia, Dingli, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400333/ https://www.ncbi.nlm.nih.gov/pubmed/30835721 http://dx.doi.org/10.1371/journal.pcbi.1006773 |
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