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Profile of the tprK gene in primary syphilis patients based on next-generation sequencing

BACKGROUND: The highly variable tprK gene of Treponema pallidum has been acknowledged to be one of the mechanisms that causes persistent infection. Previous studies have mainly focused on the heterogeneity in tprK in propagated strains using a clone-based Sanger approach. Few studies have investigat...

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Detalles Bibliográficos
Autores principales: Liu, Dan, Tong, Man-Li, Luo, Xi, Liu, Li-Li, Lin, Li-Rong, Zhang, Hui-Lin, Lin, Yong, Niu, Jian-Jun, Yang, Tian-Ci
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400401/
https://www.ncbi.nlm.nih.gov/pubmed/30789907
http://dx.doi.org/10.1371/journal.pntd.0006855