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Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen
Throughout the last several decades, vaccination has been key to prevent and eradicate infectious diseases. However, many pathogens (e.g., respiratory syncytial virus [RSV], influenza, dengue, and others) have resisted vaccine development efforts, largely because of the failure to induce potent anti...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400402/ https://www.ncbi.nlm.nih.gov/pubmed/30789898 http://dx.doi.org/10.1371/journal.pbio.3000164 |