Preparation of Polyfunctional Naphthyridines by Cobalt-Catalyzed Cross-Couplings of Halogenated Naphthyridines with Magnesium and Zinc Organometallics

[Image: see text] CoCl(2) (5%) catalyzes cross-couplings of various halogenated naphthyridines with alkyl- and arylmagnesium halides. Also, arylzinc halides undergo smooth cross-couplings with various naphthyridines in the presence of CoCl(2)·2LiCl (5%) and sodium formate (50%), leading to polyfunct...

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Autores principales: Greiner, Robert, Ziegler, Dorothée S., Cibu, Denise, Jakowetz, Andreas C., Auras, Florian, Bein, Thomas, Knochel, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400433/
https://www.ncbi.nlm.nih.gov/pubmed/29152984
http://dx.doi.org/10.1021/acs.orglett.7b03242
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author Greiner, Robert
Ziegler, Dorothée S.
Cibu, Denise
Jakowetz, Andreas C.
Auras, Florian
Bein, Thomas
Knochel, Paul
author_facet Greiner, Robert
Ziegler, Dorothée S.
Cibu, Denise
Jakowetz, Andreas C.
Auras, Florian
Bein, Thomas
Knochel, Paul
author_sort Greiner, Robert
collection PubMed
description [Image: see text] CoCl(2) (5%) catalyzes cross-couplings of various halogenated naphthyridines with alkyl- and arylmagnesium halides. Also, arylzinc halides undergo smooth cross-couplings with various naphthyridines in the presence of CoCl(2)·2LiCl (5%) and sodium formate (50%), leading to polyfunctional arylated naphthyridines. Two of these arylated naphthyridines are highly fluorescent, with quantum efficiencies reaching 95% and long excited-state lifetimes of up to 12 ns.
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spelling pubmed-64004332019-03-06 Preparation of Polyfunctional Naphthyridines by Cobalt-Catalyzed Cross-Couplings of Halogenated Naphthyridines with Magnesium and Zinc Organometallics Greiner, Robert Ziegler, Dorothée S. Cibu, Denise Jakowetz, Andreas C. Auras, Florian Bein, Thomas Knochel, Paul Org Lett [Image: see text] CoCl(2) (5%) catalyzes cross-couplings of various halogenated naphthyridines with alkyl- and arylmagnesium halides. Also, arylzinc halides undergo smooth cross-couplings with various naphthyridines in the presence of CoCl(2)·2LiCl (5%) and sodium formate (50%), leading to polyfunctional arylated naphthyridines. Two of these arylated naphthyridines are highly fluorescent, with quantum efficiencies reaching 95% and long excited-state lifetimes of up to 12 ns. American Chemical Society 2017-11-20 2017-12-01 /pmc/articles/PMC6400433/ /pubmed/29152984 http://dx.doi.org/10.1021/acs.orglett.7b03242 Text en Copyright © 2017 American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes.
spellingShingle Greiner, Robert
Ziegler, Dorothée S.
Cibu, Denise
Jakowetz, Andreas C.
Auras, Florian
Bein, Thomas
Knochel, Paul
Preparation of Polyfunctional Naphthyridines by Cobalt-Catalyzed Cross-Couplings of Halogenated Naphthyridines with Magnesium and Zinc Organometallics
title Preparation of Polyfunctional Naphthyridines by Cobalt-Catalyzed Cross-Couplings of Halogenated Naphthyridines with Magnesium and Zinc Organometallics
title_full Preparation of Polyfunctional Naphthyridines by Cobalt-Catalyzed Cross-Couplings of Halogenated Naphthyridines with Magnesium and Zinc Organometallics
title_fullStr Preparation of Polyfunctional Naphthyridines by Cobalt-Catalyzed Cross-Couplings of Halogenated Naphthyridines with Magnesium and Zinc Organometallics
title_full_unstemmed Preparation of Polyfunctional Naphthyridines by Cobalt-Catalyzed Cross-Couplings of Halogenated Naphthyridines with Magnesium and Zinc Organometallics
title_short Preparation of Polyfunctional Naphthyridines by Cobalt-Catalyzed Cross-Couplings of Halogenated Naphthyridines with Magnesium and Zinc Organometallics
title_sort preparation of polyfunctional naphthyridines by cobalt-catalyzed cross-couplings of halogenated naphthyridines with magnesium and zinc organometallics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400433/
https://www.ncbi.nlm.nih.gov/pubmed/29152984
http://dx.doi.org/10.1021/acs.orglett.7b03242
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