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Recommendations on Collecting and Storing Samples for Genetic Studies in Hearing and Tinnitus Research

OBJECTIVES: Research on the genetic basis of tinnitus is still in its first steps. A group of scientists dedicated to tinnitus genetics within European Tinnitus Network (TINNET) network recognize that further progress requires multicenter collaborative efforts for defining contributing genes. The pu...

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Autores principales: Szczepek, Agnieszka J., Frejo, Lidia, Vona, Barbara, Trpchevska, Natalia, Cederroth, Christopher R., Caria, Helena, Lopez-Escamez, Jose A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Williams And Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400449/
https://www.ncbi.nlm.nih.gov/pubmed/29889665
http://dx.doi.org/10.1097/AUD.0000000000000614
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author Szczepek, Agnieszka J.
Frejo, Lidia
Vona, Barbara
Trpchevska, Natalia
Cederroth, Christopher R.
Caria, Helena
Lopez-Escamez, Jose A.
author_facet Szczepek, Agnieszka J.
Frejo, Lidia
Vona, Barbara
Trpchevska, Natalia
Cederroth, Christopher R.
Caria, Helena
Lopez-Escamez, Jose A.
author_sort Szczepek, Agnieszka J.
collection PubMed
description OBJECTIVES: Research on the genetic basis of tinnitus is still in its first steps. A group of scientists dedicated to tinnitus genetics within European Tinnitus Network (TINNET) network recognize that further progress requires multicenter collaborative efforts for defining contributing genes. The purpose of the present work is to provide instructions regarding collection, processing, storage, and shipment of samples intended for genetic studies in auditory research. DESIGN: One part of the recommendations has a general character; another part is of particular importance for auditory healthcare practitioners such as otolaryngology physicians, audiologists, and general practitioners. RESULTS: We provide a set of instructions and various options for obtaining samples. We give advice regarding sample processing, storage, and shipment and define the minimal and essential clinical information that should accompany the samples collected for genetic processing. CONCLUSIONS: These recommendations offer a basis to standardize and optimize collaborations between geneticists and healthcare practitioners specialized in tinnitus and hearing disorders.
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spelling pubmed-64004492019-03-16 Recommendations on Collecting and Storing Samples for Genetic Studies in Hearing and Tinnitus Research Szczepek, Agnieszka J. Frejo, Lidia Vona, Barbara Trpchevska, Natalia Cederroth, Christopher R. Caria, Helena Lopez-Escamez, Jose A. Ear Hear Perspectives OBJECTIVES: Research on the genetic basis of tinnitus is still in its first steps. A group of scientists dedicated to tinnitus genetics within European Tinnitus Network (TINNET) network recognize that further progress requires multicenter collaborative efforts for defining contributing genes. The purpose of the present work is to provide instructions regarding collection, processing, storage, and shipment of samples intended for genetic studies in auditory research. DESIGN: One part of the recommendations has a general character; another part is of particular importance for auditory healthcare practitioners such as otolaryngology physicians, audiologists, and general practitioners. RESULTS: We provide a set of instructions and various options for obtaining samples. We give advice regarding sample processing, storage, and shipment and define the minimal and essential clinical information that should accompany the samples collected for genetic processing. CONCLUSIONS: These recommendations offer a basis to standardize and optimize collaborations between geneticists and healthcare practitioners specialized in tinnitus and hearing disorders. Williams And Wilkins 2019 2019-02-27 /pmc/articles/PMC6400449/ /pubmed/29889665 http://dx.doi.org/10.1097/AUD.0000000000000614 Text en Copyright © 2018 The Authors. Ear & Hearing is published on behalf of the American Auditory Society, by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Perspectives
Szczepek, Agnieszka J.
Frejo, Lidia
Vona, Barbara
Trpchevska, Natalia
Cederroth, Christopher R.
Caria, Helena
Lopez-Escamez, Jose A.
Recommendations on Collecting and Storing Samples for Genetic Studies in Hearing and Tinnitus Research
title Recommendations on Collecting and Storing Samples for Genetic Studies in Hearing and Tinnitus Research
title_full Recommendations on Collecting and Storing Samples for Genetic Studies in Hearing and Tinnitus Research
title_fullStr Recommendations on Collecting and Storing Samples for Genetic Studies in Hearing and Tinnitus Research
title_full_unstemmed Recommendations on Collecting and Storing Samples for Genetic Studies in Hearing and Tinnitus Research
title_short Recommendations on Collecting and Storing Samples for Genetic Studies in Hearing and Tinnitus Research
title_sort recommendations on collecting and storing samples for genetic studies in hearing and tinnitus research
topic Perspectives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400449/
https://www.ncbi.nlm.nih.gov/pubmed/29889665
http://dx.doi.org/10.1097/AUD.0000000000000614
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