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HIV-1 nuclear import in macrophages is regulated by CPSF6-capsid interactions at the nuclear pore complex

Nuclear entry of HIV-1 replication complexes through intact nuclear pore complexes is critical for successful infection. The host protein cleavage-and-polyadenylation-specificity-factor-6 (CPSF6) has been implicated in different stages of early HIV-1 replication. Applying quantitative microscopy of...

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Detalles Bibliográficos
Autores principales: Bejarano, David Alejandro, Peng, Ke, Laketa, Vibor, Börner, Kathleen, Jost, K Laurence, Lucic, Bojana, Glass, Bärbel, Lusic, Marina, Müller, Barbara, Kräusslich, Hans-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400501/
https://www.ncbi.nlm.nih.gov/pubmed/30672737
http://dx.doi.org/10.7554/eLife.41800

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