Cargando…
Interferon-induced guanylate-binding proteins: Guardians of host defense in health and disease
Guanylate-binding proteins (GBPs) have recently emerged as central orchestrators of immunity to infection, inflammation, and neoplastic diseases. Within numerous host cell types, these IFN-induced GTPases assemble into large nanomachines that execute distinct host defense activities against a wide v...
Autores principales: | Tretina, Kyle, Park, Eui-Soon, Maminska, Agnieszka, MacMicking, John D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400534/ https://www.ncbi.nlm.nih.gov/pubmed/30755454 http://dx.doi.org/10.1084/jem.20182031 |
Ejemplares similares
-
Guanylate-Binding Proteins (GBPs) convert cytosolic bacteria into caspase-4 signaling platforms
por: Wandel, Michal P., et al.
Publicado: (2020) -
Interferon-inducible effector mechanisms in cell-autonomous immunity
por: MacMicking, John D.
Publicado: (2012) -
NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages
por: Matta, Sumit K., et al.
Publicado: (2018) -
Guanylate-binding Protein 1 (Gbp1) Contributes to Cell-autonomous Immunity against Toxoplasma gondii
por: Selleck, Elizabeth M., et al.
Publicado: (2013) -
Rapid Interferon γ–dependent Clearance of Influenza A Virus and Protection from Consolidating Pneumonitis in Nitric Oxide Synthase 2–deficient Mice
por: Karupiah, Gunasegaran, et al.
Publicado: (1998)