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The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection

T cell development is critically dependent on successful rearrangement of antigen-receptor chains. At the β-selection checkpoint, only cells with a functional rearrangement continue in development. However, how nonselected T cells proceed in their dead-end fate is not clear. We identified low CD27 e...

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Detalles Bibliográficos
Autores principales:	Klein, Fabian, Mitrovic, Mladen, Roux, Julien, Engdahl, Corinne, von Muenchow, Lilly, Alberti-Servera, Llucia, Fehling, Hans Jörg, Pelczar, Pawel, Rolink, Antonius, Tsapogas, Panagiotis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400535/ https://www.ncbi.nlm.nih.gov/pubmed/30765463 http://dx.doi.org/10.1084/jem.20181444

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