Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer

High-grade serous ovarian cancer (HGSOC) is hallmarked by early onset of peritoneal dissemination, which distinguishes it from low-grade serous ovarian cancer (LGSOC). Here, we describe the aggressive nature of HGSOC ascitic tumor cells (ATCs) characterized by integrin α5(high) (ITGA5(high)) ATCs, w...

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Detalles Bibliográficos
Autores principales: Gao, Qinglei, Yang, Zongyuan, Xu, Sen, Li, Xiaoting, Yang, Xin, Jin, Ping, Liu, Yi, Zhou, Xiaoshui, Zhang, Taoran, Gong, Cheng, Wei, Xiao, Liu, Dan, Sun, Chaoyang, Chen, Gang, Hu, Junbo, Meng, Li, Zhou, Jianfeng, Sawada, Kenjiro, Fruscio, Robert, Grunt, Thomas W., Wischhusen, Jörg, Vargas-Hernández, Víctor Manuel, Pothuri, Bhavana, Coleman, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400537/
https://www.ncbi.nlm.nih.gov/pubmed/30710055
http://dx.doi.org/10.1084/jem.20180765

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