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Die another way: Ferroptosis drives tuberculosis pathology

In this issue of JEM, Amaral et al. (https://doi.org/10.1084/jem.20181776) provide the first evidence that ferroptosis, a newly described form of regulated cell death, is detrimental for the host during a Mycobacterium tuberculosis infection. This finding has important implications for the developme...

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Detalles Bibliográficos
Autores principales: Meunier, Etienne, Neyrolles, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400539/
https://www.ncbi.nlm.nih.gov/pubmed/30787032
http://dx.doi.org/10.1084/jem.20190038
Descripción
Sumario:In this issue of JEM, Amaral et al. (https://doi.org/10.1084/jem.20181776) provide the first evidence that ferroptosis, a newly described form of regulated cell death, is detrimental for the host during a Mycobacterium tuberculosis infection. This finding has important implications for the development of host-directed therapies for tuberculosis.