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Tumoral EHF predicts the efficacy of anti-PD1 therapy in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is a highly immune-suppressive tumor with a low response rate to single checkpoint blockade therapy. ETS homologous factor (EHF) is a tumor suppressor in PDAC. Here, we report a novel function of EHF in pancreatic cancer immune microenvironment editing and eff...
Autores principales: | Liu, Jing, Jiang, Wenna, Zhao, Kaili, Wang, Hongwei, Zhou, Tianxing, Bai, Weiwei, Wang, Xiuchao, Zhao, Tiansuo, Huang, Chongbiao, Gao, Song, Qin, Tai, Yu, Wenwen, Yang, Bo, Li, Xin, Fu, Danqi, Tan, Wei, Yang, Shengyu, Ren, He, Hao, Jihui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400540/ https://www.ncbi.nlm.nih.gov/pubmed/30733283 http://dx.doi.org/10.1084/jem.20180749 |
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