Stand by me(mory): Chronic infection diminishes memory pool via IL-6/STAT1

Despite great efforts to eradicate chronic viral infections, they still remain a global health problem. In this issue, Barnstorf et al. (2019. J. Exp. Med. https://doi.org/10.1084/jem.20181589) show that virus-unspecific bystander memory T cells are highly affected during chronic viral infection via...

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Detalles Bibliográficos
Autores principales: Lang, Philipp A., Lang, Karl S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400542/
https://www.ncbi.nlm.nih.gov/pubmed/30782615
http://dx.doi.org/10.1084/jem.20190066
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author Lang, Philipp A.
Lang, Karl S.
author_facet Lang, Philipp A.
Lang, Karl S.
author_sort Lang, Philipp A.
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description Despite great efforts to eradicate chronic viral infections, they still remain a global health problem. In this issue, Barnstorf et al. (2019. J. Exp. Med. https://doi.org/10.1084/jem.20181589) show that virus-unspecific bystander memory T cells are highly affected during chronic viral infection via IL-6/STAT1. Bystander memory T cells are strongly decimated in numbers and change in phenotype and function during chronic viral infection. These data provide new explanations for immune-mediated problems during chronic virus infections.
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spelling pubmed-64005422019-09-04 Stand by me(mory): Chronic infection diminishes memory pool via IL-6/STAT1 Lang, Philipp A. Lang, Karl S. J Exp Med News Despite great efforts to eradicate chronic viral infections, they still remain a global health problem. In this issue, Barnstorf et al. (2019. J. Exp. Med. https://doi.org/10.1084/jem.20181589) show that virus-unspecific bystander memory T cells are highly affected during chronic viral infection via IL-6/STAT1. Bystander memory T cells are strongly decimated in numbers and change in phenotype and function during chronic viral infection. These data provide new explanations for immune-mediated problems during chronic virus infections. Rockefeller University Press 2019-03-04 /pmc/articles/PMC6400542/ /pubmed/30782615 http://dx.doi.org/10.1084/jem.20190066 Text en © 2019 Lang and Lang http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle News
Lang, Philipp A.
Lang, Karl S.
Stand by me(mory): Chronic infection diminishes memory pool via IL-6/STAT1
title Stand by me(mory): Chronic infection diminishes memory pool via IL-6/STAT1
title_full Stand by me(mory): Chronic infection diminishes memory pool via IL-6/STAT1
title_fullStr Stand by me(mory): Chronic infection diminishes memory pool via IL-6/STAT1
title_full_unstemmed Stand by me(mory): Chronic infection diminishes memory pool via IL-6/STAT1
title_short Stand by me(mory): Chronic infection diminishes memory pool via IL-6/STAT1
title_sort stand by me(mory): chronic infection diminishes memory pool via il-6/stat1
topic News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400542/
https://www.ncbi.nlm.nih.gov/pubmed/30782615
http://dx.doi.org/10.1084/jem.20190066
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